Field studies were conducted to determine the effect of soybean cultivar, tillage, and rye mulch on sicklepod growth. Early-season sicklepod height was not affected by tillage or mulch. Sicklepod was tallest when grown with ‘Centennial’ or ‘Biloxi,’ the tallest cultivars, and shortest when grown with a dwarf isoline of ‘Tracy M,’ the shortest cultivar. Soybean competition reduced early-season weed density by 30 to 50%, depending on the cultivar. Centennial and dwarf Tracy M caused a 30% reduction in early-season sicklepod biomass while ‘Sharkey’ and Biloxi reduced sicklepod growth by 40%. By late-season, sicklepod biomass reduction ranged from 18% (Tracy M) to 55% (Biloxi) and was directly related to soybean cultivar height. Mulch or no-tillage independently reduced sicklepod biomass.